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    Understanding Heterogeneity in the Pathogenesis and Drug Responses of Ulcerative Colitis through Single-Cell and Spatial Transcriptomics: A Systematic Review

    Executive Summary Ulcerative colitis (UC) is a complex inflammatory bowel disease characterized by significant clinical heterogeneity, driven by intricate interactions among immune, stromal, and epithelial cells. Recent advancements in single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) have provided unprecedented…

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